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NOTICE: Classes canceled today due to weather conditions. Check Blackboard for communication from your instructors.

Jacob Immel, Ph.D.

Education

Ph.D. in Medicinal Chemistry, The University of Kansas
Dissertation: Photoredox-mediated Incorporation of Unnatural Amino Acids and the Development of a HIV-1 Packaging Inhibitor

B.S. in Chemistry, ±«Óãtv

Selected Publications

Immel, J. R.; Chen, P.-H.; McDonald, P.; Roy, A.; Johnson, D.; Bloom, S. A Priori Design, Combinatorial Synthesis, and Assessment of an Antipackaging Peptide Against Human Immunodeficiency Virus 1: Functional Role of Unnatural Trp Mimetics and Serendipitous Discovery of a Protease Inhibitor. ChemMedChem 2026, 21 (13), e70372. .

Immel, J. R.; Alghafli, B. M.; Rodríguez Ugalde, A. A.; Bloom, S. Aqueous Flavin Photoredox Catalysis Drives Exclusive C3-Alkylation of Indolyl Radical Cations in Route to Unnatural Tryptophan Mimetics. Org. Lett. 2023, 25 (20), 3818–3822. .

Immel, J. R; Bloom, S. carba-Nucleopeptides (cNPs): A Biopharmaceutical Modality Formed through Aqueous Rhodamine B Photoredox Catalysis. Angew. Chem.Int. Ed. 2022, e202205606.

Chilamari, M.; Immel, J. R; Chen, P.; Alghafli, B.; Bloom, S. Flavin Metallaphotoredox Catalysis: Synergistic Synthesis in Water.
ACS Catal. 2022, 12, 4175-4181.

Immel, J. R; Chilamari, M..; Bloom, S. Combining Flavin Photocatalysis with Parallel Synthesis: A General Platform to Optimize Peptides with Non-Proteinogenic Amino Acids. Chem. Sci. 2021, 12, 10083.

Professional Organizations

American Chemistry Society

Sigma Zeta - Math and Science National Honor Society

Church/Community Service

The Heights Church - Bolivar, MO